Wonders

Key research papers on cognitive behavioral therapy (CBT)

Landmark trials, the reviews of meta-analyses, and the internet-delivered CBT literature, with search strings that handle the behavioural/behavioral spelling split.

Data from OpenAlex, retrieved September 21, 2026

In short

Fordham et al. (2021) note that the majority of psychological treatment research investigates CBT, so the most useful entry points are reviews of meta-analyses: Butler et al. (2006), Hofmann et al. (2012) and, most recently, Cuijpers et al. (2023) and Fordham et al. (2021). Internet-delivered CBT is the largest strand among the most-cited works, from Spek et al. (2007) to Karyotaki et al. (2021). Always search both spellings, behavioral and behavioural.

How the literature is organised

The CBT literature is organised by condition and by delivery format far more than by theory. For each disorder there is a sequence: a treatment model, randomised trials, then meta-analyses. Fairburn, Cooper and Shafran (2003) is an example of the first step, a transdiagnostic model for eating disorders. Two large trials of the 2000s, the TADS trial (March et al., 2004) for adolescent depression and Walkup et al. (2008) for childhood anxiety, compared CBT with medication and with the combination.

Because there are so many meta-analyses, the most-cited papers are reviews of them: Butler et al. (2006) and Hofmann et al. (2012). Start there, find your condition and follow the references.

Main debates

The live questions are about comparison and mechanism. Is CBT better than other therapies or than medication, or merely as good? Cuijpers et al. (2023) address this for depression: CBT was more effective than other psychotherapies, but the difference was small and not significant in most sensitivity analyses, and it did not differ significantly from pharmacotherapy in the short term. Which components do the work? Furukawa et al. (2021) took internet CBT for depression apart to find out, and Furukawa et al. (2024) do the same for insomnia.

Where recent work is heading

Delivery is a major theme. Internet-based CBT produced overall effects equivalent to face-to-face treatment in the meta-analysis by Carlbring et al. (2018), a comparison updated by Hedman-Lagerlöf et al. (2023). The most-cited recent paper, Karyotaki et al. (2021), pooled individual patient data on guided and unguided internet CBT for depression and found both more effective than control conditions, with guided more effective than unguided. Chatbot delivery is represented by Fitzpatrick et al. (2017) and Jang et al. (2021), and CBT for insomnia in people with mental or physical comorbidities has produced several well-cited reviews.

Most-cited foundational papers

Published before 2021 and ranked by how often later work cites them. Read the abstract of each and the full text of the three or four closest to your question. Citation count measures attention, not quality, so treat this as a map of what the field has argued about rather than a ranking of what is true.

  1. 1
    The Efficacy of Cognitive Behavioral Therapy: A Review of Meta-analyses

    Stefan G. Hofmann and 4 others (2012). Cognitive Therapy and Research.

    Cited by 3,467Open accessdoi:10.1007/s10608-012-9476-1

  2. 2
    Cognitive behaviour therapy for eating disorders: a “transdiagnostic” theory and treatment

    Christopher G Fairburn, Zafra Cooper, Roz Shafran (2003). Behaviour Research and Therapy.

    Cited by 3,410doi:10.1016/s0005-7967(02)00088-8

  3. 3
    The empirical status of cognitive-behavioral therapy: A review of meta-analyses

    Andrew C. Butler and 3 others (2006). Clinical Psychology Review.

    Cited by 3,257doi:10.1016/j.cpr.2005.07.003

  4. 4
    Delivering Cognitive Behavior Therapy to Young Adults With Symptoms of Depression and Anxiety Using a Fully Automated Conversational Agent (Woebot): A Randomized Controlled Trial

    Kathleen Kara Fitzpatrick, Alison Darcy, Molly Vierhile (2017). JMIR Mental Health.

    Cited by 2,792Open accessdoi:10.2196/mental.7785

  5. 5
    Fluoxetine, Cognitive-Behavioral Therapy, and Their Combination for Adolescents With Depression: Treatment for Adolescents With Depression Study (TADS) Randomized Controlled Trial

    John March and 10 others (2004). JAMA.

    Cited by 1,755Open accessdoi:10.1001/jama.292.7.807

  6. 6
    Internet-based cognitive behaviour therapy for symptoms of depression and anxiety: a meta-analysis

    Viola Spek and 5 others (2007). Psychological Medicine.

    Cited by 1,645Open accessdoi:10.1017/s0033291706008944

  7. 7
    Systematic review and meta-analysis of randomized controlled trials of cognitive behaviour therapy and behaviour therapy for chronic pain in adults, excluding headache

    Stephen Morley, Christopher Eccleston, Amanda Williams (1999). Pain.

    Cited by 1,600doi:10.1016/s0304-3959(98)00255-3

  8. 8
    Cognitive Behavioral Therapy, Sertraline, or a Combination in Childhood Anxiety

    John T. Walkup and 12 others (2008). New England Journal of Medicine.

    Cited by 1,455Open accessdoi:10.1056/nejmoa0804633

  9. 9
    Cognitive-Behavioral Therapy for Adult Anxiety Disorders: A Meta-Analysis of Randomized Placebo-Controlled Trials

    Stefan G. Hoffman, Jasper A. J. Smits (2008). The Journal of Clinical Psychiatry.

    Cited by 1,433Open accessdoi:10.4088/jcp.v69n0415

  10. 10
    Internet-based vs. face-to-face cognitive behavior therapy for psychiatric and somatic disorders: an updated systematic review and meta-analysis

    Per Carlbring and 4 others (2018). Cognitive Behaviour Therapy.

    Cited by 1,341Open accessdoi:10.1080/16506073.2017.1401115

Most-cited papers since 2021

Primary studies and conceptual papers from 2021 onwards. A paper published in 2024 has had a few years to accumulate citations where the works in the section above have had decades, so compare these counts with each other rather than with the ones above.

  1. 1
    Internet-Based Cognitive Behavioral Therapy for Depression: A Systematic Review and Individual Patient Data Network Meta-analysis

    Eirini Karyotaki and 72 others (2021). JAMA Psychiatry.

    Cited by 926Open accessdoi:10.1001/jamapsychiatry.2020.4364

  2. 2
    Cognitive behavior therapy vs. control conditions, other psychotherapies, pharmacotherapies and combined treatment for depression: a comprehensive meta‐analysis including 409 trials with 52,702 patients

    Pim Cuijpers and 6 others (2023). World Psychiatry.

    Cited by 346Open accessdoi:10.1002/wps.21069

  3. 3
    Cognitive–behavioral therapy for management of mental health and stress-related disorders: Recent advances in techniques and technologies

    Mutsuhiro Nakao, Kentaro Shirotsuki, Nagisa Sugaya (2021). BioPsychoSocial Medicine.

    Cited by 334Open accessdoi:10.1186/s13030-021-00219-w

  4. 4
    Comparison of a Single-Session Pain Management Skills Intervention With a Single-Session Health Education Intervention and 8 Sessions of Cognitive Behavioral Therapy in Adults With Chronic Low Back Pain: A Randomized Clinical Trial

    Beth D. Darnall and 15 others (2021). JAMA Network Open.

    Cited by 196Open accessdoi:10.1001/jamanetworkopen.2021.13401

  5. 5
    The Efficacy of Computerized Cognitive Behavioral Therapy for Depressive and Anxiety Symptoms in Patients With COVID-19: Randomized Controlled Trial

    Zhifen Liu and 13 others (2021). Journal of Medical Internet Research.

    Cited by 174Open accessdoi:10.2196/26883

  6. 6
    Components and Delivery Formats of Cognitive Behavioral Therapy for Chronic Insomnia in Adults: A Systematic Review and Component Network Meta-Analysis

    Yuki Furukawa and 13 others (2024). JAMA Psychiatry.

    Cited by 162Open accessdoi:10.1001/jamapsychiatry.2023.5060

  7. 7
    Mobile app-based chatbot to deliver cognitive behavioral therapy and psychoeducation for adults with attention deficit: A development and feasibility/usability study

    Sooah Jang and 5 others (2021). International Journal of Medical Informatics.

    Cited by 161Open accessdoi:10.1016/j.ijmedinf.2021.104440

  8. 8
    Efficacy of Cognitive-Behavioral Therapy Targeting Severe Fatigue Following Coronavirus Disease 2019: Results of a Randomized Controlled Trial

    Tanja A Kuut and 19 others (2023). Clinical Infectious Diseases.

    Cited by 155Open accessdoi:10.1093/cid/ciad257

Recent reviews and meta-analyses

The fastest way into a literature. A good review gives you the structure of the field, a reference list to mine and, in its limitations section, the gaps other researchers have already spotted.

  1. 1
    Cognitive behavioral therapy for insomnia in patients with mental disorders and comorbid insomnia: A systematic review and meta-analysis

    Elisabeth Hertenstein and 14 others (2022). Sleep Medicine Reviews.

    Cited by 390Open accessdoi:10.1016/j.smrv.2022.101597

  2. 2
    Dismantling, optimising, and personalising internet cognitive behavioural therapy for depression: a systematic review and component network meta-analysis using individual participant data

    Toshi A Furukawa and 79 others (2021). The Lancet Psychiatry.

    Cited by 279Open accessdoi:10.1016/s2215-0366(21)00077-8

  3. 3
    Therapist‐supported Internet‐based cognitive behaviour therapy yields similar effects as face‐to‐face therapy for psychiatric and somatic disorders: an updated systematic review and meta‐analysis

    Erik Hedman‐Lagerlöf and 5 others (2023). World Psychiatry.

    Cited by 270Open accessdoi:10.1002/wps.21088

  4. 4
    Cognitive behavioural therapy with exposure and response prevention in the treatment of obsessive-compulsive disorder: A systematic review and meta-analysis of randomised controlled trials

    Jemma E. Reid and 6 others (2021). Comprehensive Psychiatry.

    Cited by 264Open accessdoi:10.1016/j.comppsych.2021.152223

  5. 5
    Cognitive behavioral therapy for insomnia in patients with chronic pain – A systematic review and meta-analysis of randomized controlled trials

    Janannii Selvanathan and 7 others (2021). Sleep Medicine Reviews.

    Cited by 204doi:10.1016/j.smrv.2021.101460

  6. 6
    The evidence for cognitive behavioural therapy in any condition, population or context: a meta-review of systematic reviews and panoramic meta-analysis

    Beth Fordham and 10 others (2021). Psychological Medicine.

    Cited by 185Open accessdoi:10.1017/s0033291720005292

How big the literature is, and where it is published

OpenAlex indexes 26,602 works whose title matches this topic. The chart shows how many were published each year from 2000 to 2025; the current year is left out because it is incomplete.

2000: 167 works16720002001: 206 works2002: 226 works2003: 231 works2004: 318 works2005: 342 works2006: 454 works2007: 466 works2008: 538 works2009: 562 works2010: 706 works2011: 724 works2012: 870 works2013: 1,044 works2014: 1,015 works2015: 1,034 works2016: 1,143 works2017: 1,250 works2018: 1,311 works2019: 1,468 works2020: 1,431 works2021: 1,504 works2022: 1,495 works2023: 1,549 works2024: 1,702 works2025: 1,941 works1,9412025
Show the numbers as a table
YearWorks
2000167
2001206
2002226
2003231
2004318
2005342
2006454
2007466
2008538
2009562
2010706
2011724
2012870
20131,044
20141,015
20151,034
20161,143
20171,250
20181,311
20191,468
20201,431
20211,504
20221,495
20231,549
20241,702
20251,941

Journals behind the most-cited work

Counted across the 373 most-cited works on the topic, not across everything published. Browsing recent issues of the first two or three is a reliable way to find current work that has not yet been cited much.

Sub-topics to narrow into

A thesis-sized question usually sits inside one of these, combined with a population or a setting.

How to cite these papers

Every paper above has a DOI, a part of the reference that is easy to leave out. Here is one of them, “Cognitive behaviour therapy for eating disorders: a “transdiagnostic” theory and treatment” (2003), in the two styles students ask about most:

APA 7th edition

Fairburn, C. G., Cooper, Z., & Shafran, R. (2003). Cognitive behaviour therapy for eating disorders: A “transdiagnostic” theory and treatment. Behaviour Research and Therapy, 41(5), 509–528. https://doi.org/10.1016/s0005-7967(02)00088-8

MLA 9th edition

Fairburn, Christopher G., et al. “Cognitive Behaviour Therapy for Eating Disorders: A ‘Transdiagnostic’ Theory and Treatment.” Behaviour Research and Therapy, vol. 41, no. 5, 2003, pp. 509–28, https://doi.org/10.1016/s0005-7967(02)00088-8.

Check the details against the article itself before you submit: databases, including the one behind this page, sometimes carry the online-first year rather than the volume year. Full rules and more examples are in our guides to APA, MLA, Chicago, Harvard, Vancouver and ABNT, with the rest in the citation guides. You can also format a reference from its DOI with our free citation tools.

Frequently asked questions

What is the best single source on whether CBT works?

Hofmann et al. (2012), The Efficacy of Cognitive Behavioral Therapy: A Review of Meta-analyses, is the most cited overview. For current evidence on depression specifically, Cuijpers et al. (2023) in World Psychiatry compares CBT with control conditions, other psychotherapies and medication. Fordham et al. (2021) is a meta-review across all conditions and populations.

Why do I find fewer results than expected when I search for CBT?

Usually because of spelling. British and Australian journals use behavioural and behaviour; American journals use behavioral and behavior. A wildcard such as behavio?ral works in most databases; otherwise combine all four phrases with OR.

Why are the founding books on cognitive therapy missing?

This page lists works with a DOI whose title contains cognitive behavioral (or behavioural) therapy. Books without a DOI, and works titled cognitive therapy, do not appear in a title search like that. Find them through the reference lists of Butler et al. (2006) or Hofmann et al. (2012), and check each one in a library catalogue before citing it.

How this page was made

The lists come from OpenAlex, an open index of scholarly works whose data are published under a CC0 licence, queried on September 21, 2026 for works whose title matches ("cognitive behavioral therapy" OR "cognitive behavioural therapy" OR "cognitive behavior therapy" OR "cognitive behaviour therapy"). Only works with a DOI are listed. Each one was checked against the publisher’s own record at Crossref or DataCite (title, year, first author, journal, volume and pages), and in three cases, where the publisher deposited no byline, against PubMed; anything OpenAlex or Crossref flags as retracted was left out, and an editor took out results that matched the words but not the subject. Citation counts are OpenAlex’s on that date and are usually lower than Google Scholar’s, which counts more kinds of document. Ranking by citations tells you what a field has relied on, not what is correct; several heavily cited papers on any topic are cited because later work disputes them. Books without a DOI are missing, which matters in fields where the founding text is a book.

Related research topics

Find your own gap.

Search 320M+ scholarly works on cognitive behavioral therapy, keep what matters on a board, and export the references. 14 days free. Students get 50% off.

Start with this topic →